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Related Experiment Video

Updated: May 5, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

Full-thickness laparoendoscopic colonic excision in an experimental model.

A Brigic¹, A Southgate, P Sibbons

¹Department of Surgery and; Wolfson Unit for Endoscopy, St Mark's Hospital and Academic Institute.

The British Journal of Surgery

|November 23, 2013

Summary

This study presents a new minimally invasive technique for colonic polyp removal, significantly reducing procedure time and colon removal. The preclinical results in pigs show safe and effective localized colonic excision with good healing.

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Last Updated: May 5, 2026

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Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection

Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection

Published on: January 9, 2026

Area of Science:

Minimally invasive surgery
Gastroenterology
Surgical innovation

Background:

Traditional colectomy for complex colonic polyps involves significant risks and extensive colon removal.
Current surgical procedures are lengthy (over 60 minutes) and remove large sections of the colon (10-30 cm).

Purpose of the Study:

To detail the preclinical development of a rapid, minimally invasive, limited full-thickness colonic resection technique.
To evaluate the safety and efficacy of this novel approach in a porcine model.

Main Methods:

Procedures were performed on anesthetized pigs using a simulated colonic polyp model.
Endoscopic ink injection and argon plasma coagulation marked the resection margins.
Endoscopic anchors facilitated full-thickness bowel eversion for laparoscopic stapler excision.

Main Results:

The median procedure duration was 26 minutes, with a specimen diameter of 5.1 cm.
Postoperative recovery was uneventful in survival animals, with well-healed resection sites.
Histological assessment confirmed mucosal repair and submucosal continuity without stenosis or infection.

Conclusions:

This technique enables full-thickness localized colonic excision, yielding a large specimen.
The method demonstrates adequate healing and safety in a porcine model, offering a promising alternative to colectomy.