Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

5.7K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
5.7K
Crossing Over01:30

Crossing Over

6.4K
Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I,...
6.4K
Crossing Over01:34

Crossing Over

128.7K
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
128.7K
Gene Conversion02:08

Gene Conversion

9.2K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
9.2K
Gene Conversion02:08

Gene Conversion

2.3K
2.3K
Viral Recombination00:57

Viral Recombination

22.3K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
22.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The evolutionary role of the dependence of recombination on environment : Two and three loci models.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

Linkage between loci of quantitative traits and marker loci: multi-trait analysis with a single marker.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

[Analysis of the meiotic recombination frequency in transgenic tomato hybrids expressing recA and NLS-recA-licBM3 genes].

Genetika·2012
Same author

New Diversity Arrays Technology (DArT) markers for tetraploid oat (Avena magna Murphy et Terrell) provide the first complete oat linkage map and markers linked to domestication genes from hexaploid A. sativa L.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2011
Same author

[Transgenic tomato plants expressing recA and NLS-recA-licBM3 genes as a model for studying meiotic recombination].

Genetika·2011
Same author

The dynamics of the rec-system in variable environments: haploid selection in a cyclical two-state environment.

Theoretical population biology·2006

Related Experiment Video

Updated: May 5, 2026

Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy
11:40

Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy

Published on: June 25, 2013

11.4K

Ecological aspects of the recombination problem.

A A Zhuchenko1, A B Korol

  • 1Department of Plant Genetics, Moldavian Academy of Sciences, Kishinev, USSR.

TAG. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik
|November 23, 2013
PubMed
Summary

Environmental factors influence the recombination system, balancing immediate adaptivity and genetic flexibility. This study explores how environmental changes can alter recombination rates and spectra, impacting population evolution.

More Related Videos

Subcloning Plus Insertion SPI - A Novel Recombineering Method for the Rapid Construction of Gene Targeting Vectors
09:02

Subcloning Plus Insertion SPI - A Novel Recombineering Method for the Rapid Construction of Gene Targeting Vectors

Published on: January 8, 2015

17.3K
Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

18.5K

Related Experiment Videos

Last Updated: May 5, 2026

Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy
11:40

Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy

Published on: June 25, 2013

11.4K
Subcloning Plus Insertion SPI - A Novel Recombineering Method for the Rapid Construction of Gene Targeting Vectors
09:02

Subcloning Plus Insertion SPI - A Novel Recombineering Method for the Rapid Construction of Gene Targeting Vectors

Published on: January 8, 2015

17.3K
Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

18.5K

Area of Science:

  • Evolutionary biology
  • Genetics
  • Environmental science

Background:

  • Environmental factors significantly impact biological systems.
  • Recombination is crucial for genetic variation and adaptation.
  • Existing models do not fully explain environmental influence on recombination control.

Purpose of the Study:

  • To investigate the effects of environmental factors on the recombination system.
  • To elucidate the interaction between individual (F-system) and population (R-system) adaptation.
  • To understand how environmental variations influence recombination rate and spectrum.

Main Methods:

  • Conceptual analysis of existing data on recombination control systems.
  • Introduction of a combined recombination rate and spectrum control model.
  • Examination of disturbance control and negative feedback mechanisms.

Main Results:

  • The interaction of F-system and R-system optimizes adaptivity and genetic flexibility.
  • Environmental factors directly influence the R-system (disturbance control).
  • Negative feedback mechanisms and F-system dependence modulate recombination control.

Conclusions:

  • Environmental factors play a critical role in shaping recombination patterns.
  • A hypothesis for the mechanism of environmental dependence of the recombination spectrum is proposed.
  • Understanding these interactions is key to predicting evolutionary trajectories.