Complete Genome Sequence of Universal Bacteriophage Host Strain Campylobacter jejuni subsp. jejuni PT14

Kelly J Brathwaite1, Patcharin Siringan, Joanna Moreton

  • 1Division of Food Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough, United Kingdom.

Genome Announcements
|November 23, 2013
PubMed

Insights

Campylobacter jejuni strain PT14 is a valuable tool for isolating bacteriophages and serves as a model host in phage therapy research, particularly for poultry applications.

Area of Science:

  • Microbiology
  • Virology
  • Food Safety

Background:

  • Campylobacter jejuni strain PT14 is a clinical isolate with a history of use in phage typing.
  • This strain has demonstrated utility in isolating various Campylobacter bacteriophages.
  • It serves as a model organism in phage therapy research, especially concerning poultry.

Purpose of the Study:

  • To highlight the significance of Campylobacter jejuni strain PT14 in phage research.
  • To underscore its role in bacteriophage isolation and propagation.
  • To emphasize its application as a model host in phage therapy for poultry.

Main Methods:

  • Utilizing Campylobacter jejuni strain PT14 for bacteriophage isolation from diverse sources.
  • Employing the strain as a host in phage therapy experiments.
  • Documenting its effectiveness in phage propagation within the UK phage typing scheme.

Main Results:

  • Campylobacter jejuni strain PT14 has been successfully used to isolate Campylobacter bacteriophages.
  • The strain functions effectively as a model host in phage therapy studies.
  • Its utility is established in phage propagation for the United Kingdom phage typing scheme.

Conclusions:

  • Campylobacter jejuni strain PT14 is a crucial resource for Campylobacter bacteriophage research.
  • Its role as a model host is vital for advancing phage therapy applications in poultry.
  • The strain's utility spans isolation, propagation, and therapeutic applications.

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