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Updated: May 5, 2026

Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
[Survey of renal replacement therapy in childhood with chronic renal failure]
Insights
This study analyzed renal replacement therapy for childhood chronic renal failure (CRF) in China. Hemodialysis is common, but peritoneal dialysis and transplantation are underdeveloped, indicating an imbalance in pediatric CRF treatment.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
- Chronic Renal Failure
Context:
- Childhood chronic renal failure (CRF) poses significant health challenges globally.
- Nationwide data from 2007-2011 in China provides a comprehensive overview of pediatric CRF management.
- Understanding treatment modalities and outcomes is crucial for improving care.
Purpose:
- To investigate the current status of renal replacement therapy (RRT) for children with CRF in China.
- To analyze the outcomes and complications associated with different RRT methods in pediatric patients.
- To identify disparities and areas for improvement in childhood CRF treatment.
Summary:
- A survey of 1033 hospitalized children with CRF (2007-2011) revealed that 45.9% received RRT.
- Hemodialysis was the most common (380 patients), with significant acute and chronic complications.
- Peritoneal dialysis (177 patients) and renal transplantation (40 patients) showed lower utilization and specific complication rates, including rejections.
Impact:
- Highlights the current landscape of pediatric RRT in China, emphasizing the dominance of hemodialysis.
- Identifies critical areas for development, particularly in peritoneal dialysis and pediatric renal transplantation.
- Provides essential data for policymakers and clinicians to address the imbalance in RRT for childhood CRF.
Objective:
To investigate the renal replacement therapy and outcome of chronic renal failure (CRF) in childhood, a nation-wide survey was conducted and data of hospitalized children (younger than 18 years old) with CRF during the period of 2007 to 2011 were analyzed.
Method:
Questionnaires of renal replacement therapy of patients with CRF in childhood were designed and distributed to 28 hospitals in China. The data were collected and analyzed.
Result:
There were 1033 hospitalized children with CRF from January 1, 2007 to December 31, 2011 in 28 hospitals. There were 474 patients (45.9%) received renal replacement therapy. Hemodialyses were given to 380 patients; 133 patients (35.0%) got acute complications with hemodialysis and 119 patients (31.3%) got chronic complications. Peritoneal dialysis were given to 177 patients and 79 patients got complications. Forty patients received renal transplantation and 9 patients got rejections.
Conclusion:
Renal replacement therapy in CRF in childhood has been improved but there is imbalance in China. Hemodialysis is the common way in maintenance dialysis and peritoneal dialysis is still underdeveloped. Renal transplantation in children is in the early stages.
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