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Published on: September 28, 2015
The anatomical basis of infection of the aortic root
Abstract:
Although images of large abscess cavities in the aortic root in the presence of infection may be obtained by echocardiography or angiocardiography, discrete cavitations and paravalvar leaks, especially small ones, tend to remain unrecognized. Furthermore the abscesses themselves and their extent are often difficult to locate at operation, and it is this difficulty in delineating paravalvar foci of destruction which remains a major surgical challenge in aortic infections. The inability of current imaging techniques to elucidate this problem is compounded by the limited access which aortotomy gives to the aortic root. In the case of prosthetic valve endocarditis, the aortic root is often distorted, this distortion is greater where more than one prosthetic valve has been used, so that identification of septic areas and abscess cavities may further be obfuscated. Five necropsy specimens of normal hearts and 10 with infective endocarditis of either natural or prosthetic valves in either aortic or atrioventricular position were studied to elucidate the anatomy of the aortic root and to identify sites of potential abscess formation and of rupture.
Insights
Detecting small aortic root abscesses and paravalv alvar leaks is challenging with current imaging. This study investigates aortic root anatomy to improve identification of infection sites and potential rupture points.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Medical Imaging
Background:
- Large aortic root abscesses are visible via echocardiography or angiocardiography.
- Small paravalvular leaks and discrete cavitations are often missed by current imaging techniques.
- Locating abscesses and their extent during surgery is a significant challenge in aortic infections.
Purpose of the Study:
- To elucidate the anatomy of the aortic root.
- To identify potential sites of abscess formation.
- To identify potential sites of rupture in infective endocarditis.
Main Methods:
- Study of 5 normal necropsy heart specimens.
- Study of 10 necropsy heart specimens with infective endocarditis (natural or prosthetic valves).
- Examination of aortic and atrioventricular valve positions.
Main Results:
- Current imaging techniques have limitations in detecting small paravalvular leaks and abscesses.
- Aortic root distortion, especially with multiple prosthetic valves, further complicates identification of septic areas.
- Limited access via aortotomy hinders comprehensive visualization of the aortic root.
Conclusions:
- Improved understanding of aortic root anatomy is crucial for surgical planning in infective endocarditis.
- Enhanced imaging or surgical approaches are needed to better delineate paravalvular abscesses and leaks.
- Accurate localization of infection is vital for effective treatment and reducing surgical complications.
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