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Feline aspergillosis

Vanessa R Barrs1, Jessica J Talbot

  • 1Faculty of Veterinary Science, University Veterinary Teaching Hospital Sydney, The University of Sydney, Evelyn Williams Building, B10, Sydney, New South Wales 2006, Australia.

The Veterinary Clinics of North America. Small Animal Practice
|November 26, 2013
PubMed

Insights

Feline aspergillosis, including sino-orbital aspergillosis (SOA) and sinonasal aspergillosis (SNA), requires molecular identification for accurate diagnosis. While SNA has a good prognosis, SOA caused by Aspergillus felis carries a poor outlook.

Area of Science:

  • Veterinary Mycology
  • Infectious Diseases in Cats

Background:

  • Feline aspergillosis encompasses various forms, including sinonasal aspergillosis (SNA) and sino-orbital aspergillosis (SOA).
  • Sino-orbital aspergillosis (SOA) is an emerging invasive fungal infection in cats.
  • Aspergillus felis is a recently identified pathogen frequently implicated in SOA.

Purpose of the Study:

  • To differentiate between feline sinonasal aspergillosis (SNA) and sino-orbital aspergillosis (SOA).
  • To highlight the etiological agents and diagnostic requirements for these feline mycoses.
  • To compare the clinical outcomes and prognoses of SNA and SOA.

Main Methods:

  • Review of clinical cases and diagnostic findings for feline aspergillosis.
  • Emphasis on the necessity of molecular techniques for accurate fungal identification.
  • Differential diagnosis based on clinical presentation and mycology.

Main Results:

  • Sinonasal aspergillosis (SNA) is commonly caused by Aspergillus fumigatus and Aspergillus niger.
  • Sino-orbital aspergillosis (SOA) is increasingly associated with Aspergillus felis.
  • Accurate identification of fungal species causing SNA and SOA necessitates molecular methods.

Conclusions:

  • Feline aspergillosis presents with diverse clinical forms, requiring precise etiological diagnosis.
  • Sinonasal aspergillosis (SNA) generally has a favorable prognosis with appropriate treatment.
  • Sino-orbital aspergillosis (SOA) has a poorer prognosis, underscoring the need for early and accurate diagnosis.
Keywords:
AntifungalsAspergillosisAspergillus felisFungal rhinosinusitisSino-orbital aspergillosisSinonasal aspergillosis

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