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[Hemodynamic component in glaucoma and its association with risk factors and cardiovascular disease]

José Enrique Muñoz de Escalona-Rojas1, Jesús Cantero-Hinojosa2, Fermín Garrido-Pareja3

  • 1Unidad de Gestión Clínica, Hospital Universitario San Cecilio, Granada, España.

Medicina Clinica
|November 26, 2013
PubMed

Insights

Glaucoma is linked to cardiovascular disease (CVD) and impaired ocular blood flow. Patients with primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) show more cardiovascular risks and poorer ocular perfusion.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Vascular Biology

Context:

  • Glaucoma is a leading cause of irreversible blindness.
  • Cardiovascular disease (CVD) and ocular hemodynamic variables (OHV) are potential risk factors for glaucoma.
  • Understanding the interplay between systemic vascular health and ocular perfusion is crucial for glaucoma management.

Purpose:

  • To investigate the association between glaucoma and cardiovascular disease (CVD).
  • To examine ocular hemodynamic variables (OHV) in patients with glaucoma.
  • To explore the relationship between cardiovascular risk factors (CVRF) and glaucoma.

Summary:

  • A cross-sectional study of 73 patients (25 controls, 28 with primary open-angle glaucoma (POAG), 20 with normal-tension glaucoma (NTG)) assessed CVRF, CVD, and OHV.
  • Patients with POAG and NTG exhibited a higher prevalence of CVRF and CVD compared to controls.
  • Glaucoma patients demonstrated altered OHV, including reduced blood flow velocities and increased vascular resistance in ocular arteries.

Impact:

  • The findings highlight a significant association between CVD/CVRF and glaucoma.
  • Altered OHV in glaucoma patients suggest compromised ocular perfusion.
  • This research underscores the importance of considering systemic vascular health in the context of glaucoma.
Abstract

Keywords:
Cardiovascular diseasesEnfermedades cardiovascularesFactores de riesgoGlaucomaRisk factors

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