Related Experiment Video

Updated: May 5, 2026

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
06:19

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology

Published on: May 31, 2024

1.9K

[Subretinal neovascular membrane in angioid streaks treated with intravitreal bevacizumab]

A García-López1, C González-Castaño1

  • 1Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.

Archivos De La Sociedad Espanola De Oftalmologia
|November 26, 2013
PubMed
Abstract

Insights

Intravitreal bevacizumab effectively treated subretinal neovascular membranes (SRNVM) in a patient with angioid streaks and pseudoxanthoma elasticum, improving vision. This treatment offers a promising option for associated choroidal neovascularization.

Area of Science:

  • Ophthalmology
  • Medical Genetics

Background:

  • Angioid streaks are breaks in Bruch's membrane, often linked to genetic disorders like pseudoxanthoma elasticum.
  • Subretinal neovascular membranes (SRNVM) are a common, vision-threatening complication of angioid streaks.

Observation:

  • A case report details a 28-year-old woman diagnosed with pseudoxanthoma elasticum due to angioid streaks.
  • The patient presented with SRNVM in her left eye, leading to decreased vision.

Findings:

  • Three intravitreal bevacizumab injections were administered to the affected eye.
  • Rapid visual improvement and sustained stability were observed over an 11-month follow-up period.

Implications:

  • Intravitreal bevacizumab demonstrates efficacy in managing choroidal neovascularization secondary to angioid streaks.
  • This treatment approach offers a potential therapeutic strategy for patients with pseudoxanthoma elasticum and related ocular complications.
Keywords:
Angioid streaksAnti-VEGFBevacizumab intravítreoEstrías angioidesIntravitreal bevacizumabMembrana neovascular subretinianaNeovascular subretinal membranePseudoxanthoma elasticumPseudoxantoma elástico

More Related Videos

An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy08:10

An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy

Published on: January 25, 2019

7.2K
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs10:02

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

Published on: July 23, 2016

30.6K

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.7K
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
65