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Macrophage mitochondrial damage from StAR transport of 7-hydroperoxycholesterol: implications for oxidative

Witold Korytowski1, Katarzyna Wawak2, Pawel Pabisz2

  • 1Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Biophysics, Jagiellonian University, Krakow, Poland.

FEBS Letters
|November 26, 2013
PubMed

Keywords:
1-palmitoyl-2-sn-glycero-3-phosphocholine3-(4,5-dimethylthiazolyl-2-yl)-2,5-diphenyltetrazolium bromide3β-hydroxycholest-5-ene-7α-hydroperoxide4,4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-inda-cene-3-undecanoic acid5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-benzimidazolylcarbocyanine iodide7α-OH7α-OOHABCA1ATP binding cassette transporter A1C11-BODIPYChOOH(s)Cholesterol hydroperoxideJC-1MTTMacrophageOxidative stressPBSPOPCReverse cholesterol transportSUV(s)StAR proteinStarD1StarD4cholest-5-ene-3β,7α-diolcholesterol hydroperoxide(s)db-cAMPdibutyryl-cAMPphosphate-buffered salinesmall unilamellar vesicle(s)type-1 steroidogenic acute regulatory domain proteintype-4 steroidogenic acute regulatory domain protein

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