Myocardial bridging as a common phenotype of hypertrophic cardiomyopathy has no effect on prognosis

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Tao Tian1, Yi-Lu Wang, Ji-Zheng Wang

  • 1Departments of Cardiology (TT, Y-LW, B-ZY, RT-H, X-LZ, LS), Sino-German Laboratory for Molecular Medicine (J-ZW, KS, W-LZ, R-TH), and Hypertension Center (RT-H, X-LZ, LS), State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; and Department of Cardiology (LZ, HS), First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, China.

The American Journal of the Medical Sciences
|November 26, 2013
PubMed

Insights

Myocardial bridging is common in hypertrophic cardiomyopathy (HCM) but does not predict adverse outcomes like death or heart failure. This finding clarifies the prognostic significance of myocardial bridging in HCM patients.

Area of Science:

  • Cardiology
  • Cardiovascular Research
  • Medical Diagnostics

Background:

  • Prognostic significance of myocardial bridging in hypertrophic cardiomyopathy (HCM) is debated.
  • This study aimed to clarify the impact of myocardial bridging on HCM patient prognosis.

Purpose of the Study:

  • To investigate the association between myocardial bridging and clinical outcomes in patients with hypertrophic cardiomyopathy.
  • To determine if myocardial bridging predicts adverse events in HCM.

Main Methods:

  • Retrospective analysis of 298 adult HCM patients (1999-2011).
  • Myocardial bridging assessed via coronary angiography.
  • Follow-up data collected through interviews and questionnaires.

Main Results:

  • Myocardial bridging identified in 11% of patients, most commonly in the left anterior descending artery.
  • Patients with bridging were younger.
  • No significant association found between myocardial bridging and all-cause death, cardiovascular death, sudden cardiac death, or heart failure deterioration.

Conclusions:

  • Myocardial bridging is a frequent finding in hypertrophic cardiomyopathy.
  • Myocardial bridging is not a predictor of adverse clinical outcomes in HCM patients.
Abstract

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