Fast and slow myosins as specific markers of muscle: an immunocytochemical study

Slow and fast myosins are specific markers of skeletal muscle. The specificity of anti-fast and anti-slow myosin antisera been verified on frozen and paraffin embedded tissues. The optimal fixative useful for routine histopathological purposes has been investigated. It is suggested that these two antisera can be used in the diagnosis of rhabdomyoblastic tumours substituting for or complementary to myoglobin, a well known marker of striated muscle.