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Published on: June 28, 2019
Myocardial revascularization in dyalitic patients: in-hospital period evaluation
Insights
Coronary artery bypass grafting (CABG) is feasible for patients on dialysis with multivessel coronary disease. However, this patient group experiences high in-hospital morbidity and mortality rates, necessitating further research into metabolic factors.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Internal Medicine
Background:
- Coronary artery bypass grafting (CABG) is the optimal treatment for patients with multivessel coronary disease requiring dialysis.
- However, the procedure is associated with significant hospital morbidity and mortality in this population.
Purpose of the Study:
- To assess the outcomes and in-hospital results of CABG in patients undergoing dialysis.
- To identify factors associated with mortality in this high-risk group.
Main Methods:
- A retrospective, single-center study was conducted.
- Included were 50 consecutive, unselected patients on dialysis who underwent CABG between 2007 and 2012 at a tertiary university hospital.
Main Results:
- Patients exhibited a high prevalence of cardiovascular risk factors: 100% were hypertensive, 68% diabetic, and 40% dyslipidemic.
- No intra-operative deaths occurred, and 60% of procedures were performed off-pump.
- Seven patients (14%) died during hospitalization. Mortality was linked to postoperative infection, prior heart failure, cardiopulmonary bypass use, impaired ventricular function, and re-exploration.
Conclusions:
- CABG is a viable option for dialysis patients with multivessel coronary disease, despite elevated in-hospital morbidity and mortality.
- Further investigation into metabolic aspects is crucial for optimizing interventions and improving patient outcomes.
Background:
Coronary artery bypass grafting currently is the best treatment for dialytic patients with multivessel coronary disease, but hospital morbidity and mortality related to procedure is still high.
Objective:
Evaluate results and in-hospital outcomes of coronary artery bypass grafting in dialytic patients.
Methods:
Retrospective unicentric study including 50 consecutive and not selected dialytic patients, who underwent coronary artery bypass grafting in a tertiary university hospital from 2007 to 2012.
Results:
High prevalence of cardiovascular risk factors was observed (100% hypertensive, 68% diabetic and 40% dyslipidemic). There was no intra-operative death and 60% of the procedures were performed off-pump. There were seven (14%) in-hospital deaths. Postoperative infection, previous heart failure, cardiopulmonary bypass, abnormal ventricular function and surgical re-exploration were associated with increased mortality.
Conclusion:
Coronary artery bypass grafting is feasible to dialytic patients although high in-hospital morbidity and mortality. It is necessary better understanding about metabolic aspects to plan adequate interventions.
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