Myocardial revascularization in dyalitic patients: in-hospital period evaluation

Insights

Coronary artery bypass grafting (CABG) is feasible for patients on dialysis with multivessel coronary disease. However, this patient group experiences high in-hospital morbidity and mortality rates, necessitating further research into metabolic factors.

Area of Science:

  • Cardiovascular Surgery
  • Nephrology
  • Internal Medicine

Background:

  • Coronary artery bypass grafting (CABG) is the optimal treatment for patients with multivessel coronary disease requiring dialysis.
  • However, the procedure is associated with significant hospital morbidity and mortality in this population.

Purpose of the Study:

  • To assess the outcomes and in-hospital results of CABG in patients undergoing dialysis.
  • To identify factors associated with mortality in this high-risk group.

Main Methods:

  • A retrospective, single-center study was conducted.
  • Included were 50 consecutive, unselected patients on dialysis who underwent CABG between 2007 and 2012 at a tertiary university hospital.

Main Results:

  • Patients exhibited a high prevalence of cardiovascular risk factors: 100% were hypertensive, 68% diabetic, and 40% dyslipidemic.
  • No intra-operative deaths occurred, and 60% of procedures were performed off-pump.
  • Seven patients (14%) died during hospitalization. Mortality was linked to postoperative infection, prior heart failure, cardiopulmonary bypass use, impaired ventricular function, and re-exploration.

Conclusions:

  • CABG is a viable option for dialysis patients with multivessel coronary disease, despite elevated in-hospital morbidity and mortality.
  • Further investigation into metabolic aspects is crucial for optimizing interventions and improving patient outcomes.
Abstract

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