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Updated: May 5, 2026

Measurement of Natural Killer Cell-Mediated Cytotoxicity and Migration in the Context of Hepatic Tumor Cells
Published on: February 22, 2020
Dendritic cell derived cytokines in human natural killer cell differentiation and activation
Obinna Chijioke1, Christian Münz
1Viral Immunobiology, Institute of Experimental Immunology, University of Zurich , Zurich , Switzerland.
Abstract:
Dendritic cells (DCs) and natural killer (NK) cells shape each other's functions early during immune responses. DCs activate NK cells and NK cells can mature or kill DCs. In this review we will discuss which DC and NK cell subsets are mainly affected by this interaction, where these encounters might take place and which signals are exchanged. Finally, we will point out what the clinical benefit of understanding this interaction might be and how it changed our view on NK cells as innate lymphocytes.
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