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Related Concept Videos

Genetic Variation01:25

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Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
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In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
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In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
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Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying...
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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
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Epigenetic variation in asexually reproducing organisms.

Koen J F Verhoeven1, Veronica Preite

  • 1Department of Terrestrial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, The Netherlands. k.verhoeven@nioo.knaw.nl.

Evolution; International Journal of Organic Evolution
|November 27, 2013
PubMed
Summary
This summary is machine-generated.

Epigenetic inheritance aids adaptation differently in asexuals versus sexuals. Asexuals may accumulate more epigenetic variation due to bypassed reprogramming, potentially enhancing adaptation.

Keywords:
ApomixisDNA methylationepigenetic resettingparthenogenesistransgenerational epigenetic inheritancevegetative propagation

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Area of Science:

  • Evolutionary biology
  • Genetics
  • Epigenetics

Background:

  • Epigenetic inheritance's role in adaptation may differ between sexual and asexual reproduction.
  • Asexual reproduction can bypass meiotic epigenetic reprogramming, potentially increasing epigenetic variation.

Purpose of the Study:

  • To evaluate evidence for epigenetic contributions to adaptation in asexual organisms.
  • To explore the relevance of epigenetics-mediated phenotypic plasticity and epimutations in asexuals.

Main Methods:

  • Review of current evidence on epigenetic inheritance in asexuals.
  • Analysis of epigenetic reprogramming mechanisms in sexual versus asexual reproduction.
  • Examination of DNA methylation, transcriptomes, and phenotypes in clonal offspring.

Main Results:

  • Some asexual reproduction modes may enhance stable transmission of epigenetic marks compared to sexual reproduction.
  • Evidence shows stable transmission of DNA methylation, transcriptomes, and phenotypes in asexual species.
  • Habitat-specific DNA methylation observed in clonal genotypes from natural populations.

Conclusions:

  • Epigenetic variation, through plasticity and epimutations, is relevant for asexual adaptation.
  • Direct experimental tests of sexual-asexual differences in epigenetic adaptation are lacking.
  • Further research can extend current observations to demonstrate epigenetic contributions to adaptation in asexuals.