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Updated: May 5, 2026

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
The interactions of nonalcoholic fatty liver disease and cardiovascular diseases
Hugo Perazzo1, Thierry Poynard, Jean-François Dufour
1Hepatology Department, Liver Center, Groupe Hospitalier Pitié-Salpêtrière (GHPS), Assistance Publique Hôpitaux de Paris (APHP), 47-83, Boulevard de l'Hôpital, Paris 75013, France; Pierre et Marie Curie University (Paris 6), Inserm UMR_S 938, Paris, France.
Abstract:
A complex interaction among metabolic factors, adipose tissue lipolysis, oxidative stress, and insulin resistance results in a deleterious process that may link nonalcoholic fatty liver disease (NAFLD) with severe cardiovascular (CV) outcomes. Patients with NAFLD are at higher risk of atherosclerosis, new onset of CV events, and overall mortality. The strong association between NAFLD and CV disease should affect clinical practice, with screening and surveillance of patients with NAFLD. This review discusses the data linking these major diseases.
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