Related Experiment Video

Updated: May 5, 2026

A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior
09:26

A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior

Published on: January 5, 2021

6.3K

Early experience of a novel-environment in isolation primes a fearful phenotype characterized by persistent amygdala

Nikolaos P Daskalakis1, Anastasia Diamantopoulou2, Sanne E F Claessens3

  • 1Division of Medical Pharmacology, Leiden Academic Center for Drug Research, Leiden University Medical Center, Leiden University, Leiden, The Netherlands; Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden University, Leiden, The Netherlands; Traumatic Stress Studies Division & Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, USA; Mental Health Care Center, PTSD Clinical Research Program and Laboratory of Clinical Neuroendocrinology and Neurochemistry, James J. Peters Veterans Affairs Medical Center, Bronx, USA.

Psychoneuroendocrinology
|November 27, 2013
PubMed

Keywords:
ACTHAmygdalaCorticosteroneFear-conditioningMaternal separationNovelty stressShort-term memorySocial playc-Fos

More Related Videos

Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder05:49

Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder

Published on: October 13, 2018

11.4K
Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats13:38

Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats

Published on: August 22, 2020

7.9K

Related Concept Videos

Role of Amygdala in Memory01:16

Role of Amygdala in Memory

The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
1.9K
Preparedness and Phobias01:09

Preparedness and Phobias

Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
477