Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

2.1K
2.1K
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

3.7K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
3.7K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.2K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.2K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.2K
5.2K
Skin Cancer01:30

Skin Cancer

5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

6.1K
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caution in Interpreting Prognostic Genomic Factors in Underpowered Subgroups of Children with T-ALL.

Blood advances·2026
Same author

Persistent <i>BCR::ABL1</i>-positive preleukemic stem cells drive late clonal evolution in Philadelphia chromosome-positive ALL.

HemaSphere·2026
Same author

Descriptive Epidemiology and Prognosis of Pediatric Acute Leukemia in the Afro-Descendant Population of the French West Indies and French Guiana.

Cancer medicine·2026
Same author

Increased Susceptibility to Long-Term Complications in Leukemia Survivors Who Received Hematopoietic Stem Cell Transplantation During Adolescence.

Transplantation and cellular therapy·2026
Same author

Genomic fusion breakpoints for DNA-based measurable residual disease monitoring in pediatric acute lymphoblastic leukemia.

Leukemia·2026
Same author

First-year results of the International Leukemia/Lymphoma Target Board for pediatric relapsed and refractory hematological malignancies.

Haematologica·2026
Same journal

Somatostatin receptor PET response assessment framework for patients with neuroendocrine tumours (V1.0): a modified Delphi consensus from the European Neuroendocrine Tumor Society (endorsed by EANM and NANETS).

The Lancet. Oncology·2026
Same journal

Differential impact of proton pump inhibitors and antibiotics on immunotherapy efficacy after chemoradiotherapy in locally advanced non-small-cell lung cancer: a post-hoc analysis of the PACIFIC trial.

The Lancet. Oncology·2026
Same journal

Co-medications and gut microbiome in NSCLC immunotherapy.

The Lancet. Oncology·2026
Same journal

Carcinogenicity of butyl benzyl phthalate, dibutyl phthalate, and diisononyl phthalate.

The Lancet. Oncology·2026
Same journal

New report sheds light on cancer disparities in the USA.

The Lancet. Oncology·2026
Same journal

Review highlights gaps in South Africa's cancer care.

The Lancet. Oncology·2026
See all related articles

Related Experiment Video

Updated: May 5, 2026

Neonatal Pial Surface Electroporation
06:22

Neonatal Pial Surface Electroporation

Published on: May 7, 2014

13.4K

Neonatal cancer.

Daniel Orbach1, Sabine Sarnacki, Hervé J Brisse

  • 1Department of Paediatric Oncology, Institut Curie, Paris, France.

The Lancet. Oncology
|November 27, 2013
PubMed
Summary
This summary is machine-generated.

Neonatal cancers are rare and diverse, often presenting differently than in older children. Management requires a multidisciplinary approach due to unique diagnostic, therapeutic, and ethical challenges in vulnerable newborns.

More Related Videos

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

3.5K
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

5.5K

Related Experiment Videos

Last Updated: May 5, 2026

Neonatal Pial Surface Electroporation
06:22

Neonatal Pial Surface Electroporation

Published on: May 7, 2014

13.4K
A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

3.5K
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

5.5K

Area of Science:

  • Oncology
  • Pediatrics
  • Neonatology

Background:

  • Neonatal cancer is a rare, heterogeneous group of neoplasms.
  • Tumor presentation and behavior in neonates differ from older children, impacting diagnosis and management.
  • Genetic factors are implicated, and congenital abnormalities are often present.

Purpose of the Study:

  • To summarize the key aspects of neonatal cancer, including its diversity, common types, diagnosis, and management challenges.
  • To highlight the unique considerations for treating cancer in the neonatal population.

Main Methods:

  • Review of existing literature on neonatal neoplasms.
  • Analysis of histological diversity and common cancer types in neonates.
  • Discussion of diagnostic modalities, including prenatal detection.
  • Examination of treatment challenges and ethical considerations.

Main Results:

  • Teratoma and neuroblastoma are the most common neonatal cancers.
  • Other frequent types include soft-tissue sarcoma, leukemia, renal, and brain tumors.
  • Prenatal detection via ultrasound is increasing.
  • Treatment is complex due to the neonate's vulnerability.

Conclusions:

  • Neonatal cancer management necessitates a multidisciplinary approach.
  • Diagnostic and therapeutic strategies must account for the unique vulnerabilities of neonates.
  • Ethical considerations are paramount in neonatal cancer care.