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Updated: May 5, 2026

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
Published on: August 26, 2011
Patterns of cortico-limbic activations during visual processing of sad faces in depression patients: a
Abstract:
The author retrieved 10 functional magnetic resonance imaging studies about visual tasks for emotional faces in subjects with depression. The activation foci were then summarized and entered into a coordinate-based meta-analysis. The depression group showed significantly increased activations in the left striatum and left parahippocampal gyrus; the control group showed increased activations in the left medial frontal gyrus, left middle frontal gyrus, right thalamus, left anterior cingulate, and superior frontal gyrus. The study suggests that depression patients have limbic activations, and controls have fronto-thalamic activations with visual processing of emotional faces.
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