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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Ankylosing spondylitis presenting with discitis.

R A Ibrahim1, N I Sarwani, S G Kanekar

  • 1Department of Medicine, Salmaniya Medical Complex, PO Box 12, Manama, Bahrain. Tel. 255555/279774. Fax. 275612.

Neurosciences (Riyadh, Saudi Arabia)
|November 27, 2013
PubMed
Summary
This summary is machine-generated.

Ankylosing spondylitis, a rare condition in Bahrain, can present as discitis. This case highlights the importance of Human Leukocyte Antigen-827 testing for diagnosing this rare presentation.

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Area of Science:

  • Rheumatology
  • Immunogenetics
  • Spinal Imaging

Background:

  • Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the axial skeleton.
  • While common globally, AS is considered rare in Bahrain.
  • Discitis, an inflammation of the intervertebral disc, is an uncommon manifestation of AS.

Purpose of the Study:

  • To report the first case of ankylosing spondylitis presenting as discitis in Bahrain.
  • To emphasize the diagnostic challenges and atypical presentations of AS.
  • To highlight the role of Human Leukocyte Antigen-827 (HLA-B27) in diagnosing AS.

Main Methods:

  • Case presentation of a patient with persistent backache.
  • Diagnostic workup including imaging and laboratory tests.
  • Genetic testing for Human Leukocyte Antigen-B27 (HLA-B27).

Main Results:

  • The patient presented with symptoms suggestive of discitis.
  • Initial diagnosis focused on discitis, with AS being considered later.
  • Positive HLA-B27 test confirmed the diagnosis of ankylosing spondylitis.
  • This represents a rare clinical presentation of AS in the region.

Conclusions:

  • Ankylosing spondylitis can manifest atypically as discitis, even in regions where it is considered rare.
  • HLA-B27 positivity is crucial for diagnosing AS, especially in unusual presentations.
  • This case underscores the need for comprehensive diagnostic evaluation in patients with chronic back pain.