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Published on: May 4, 2021
Elevated levels of exhaled nitric oxide in patients with anorexia nervosa
Joanna Oświęcimska1, Katarzyna Ziora, Dariusz Ziora
1Department of Paediatrics, Medical University of Silesia in Katowice, ul. 3 Maja 13/15, 41-800, Zabrze, Poland.
Background:
Nitric oxide (NO) is involved in eating behavior and inflammatory response. Moreover, there is evidence that NO production is altered in patients with anorexia nervosa (AN).
Aim:
To assess whether the overproduction of NO in AN can affect NO level in exhaled air.
Materials And Methods:
Exhaled NO level was studied in 23 girls with AN and compared with that of healthy age- and gender-matched nonatopic controls.
Results:
Exhaled NO levels were significantly higher in girls with AN compared with healthy age-matched controls.
Conclusions:
It appears that anorexia nervosa was accompanied by a higher level of exhaled NO, likely resulting from a systemic increase in NO production because of the severe catabolic state.
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