Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

47
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
47
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

30
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
30
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

39
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
39
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.8K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.8K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

844
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
844
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

4.5K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
4.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An unusual association between oral sarcoma and bulbar palsy.

Neurosciences (Riyadh, Saudi Arabia)·2013
Same author

An unusual association between oral sarcoma and bulbar palsy.

Saudi medical journal·2001
Same author

Intracranial tuberculoma.

Saudi medical journal·2001
Same journal

Association Between Extracranial Artery Stenosis and Cerebral Small-Vessel Disease in Patients with Ischemic Stroke.

Neurosciences (Riyadh, Saudi Arabia)·2026
Same journal

Identifying Risk Factors for the Rising Prevalence of Multiple Sclerosis in Saudi Arabia: A case-control analysis.

Neurosciences (Riyadh, Saudi Arabia)·2026
Same journal

Novel <i>ENPP</i>1 Gene Mutation Causing Generalized Arterial Calcification of Infancy: A case report.

Neurosciences (Riyadh, Saudi Arabia)·2026
Same journal

Insights Into Stroke Risk and Prediction for Underweight Individuals.

Neurosciences (Riyadh, Saudi Arabia)·2026
Same journal

Key Attributes of an Ideal Neurology Residency Candidate: Program Directors' Perspectives.

Neurosciences (Riyadh, Saudi Arabia)·2026
Same journal

Impact of Burnout and Sleep Deprivation on the Clinical Performance of Neurology Residents: A Cross-Sectional Country Wide Study.

Neurosciences (Riyadh, Saudi Arabia)·2026
See all related articles

Related Experiment Video

Updated: May 5, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.3K

Intracranial tuberculoma.

T M Zein1, P S Fletcher, Z M Mirghani

  • 1Department of Medicine and Pathology, Armed Forces Hospital, Southern Region, PO Box 101, Khamis Mushayt, Kingdom of Saudi Arabia. Tel/Fax. +00966 (7) 2511550. Fax. +00966 (7) 2247570.

Neurosciences (Riyadh, Saudi Arabia)
|November 27, 2013
PubMed
Summary
This summary is machine-generated.

Cerebral tuberculoma, a brain lesion, requires inclusion in differential diagnoses for space-occupying conditions. Magnetic resonance imaging aids diagnosis, and 12 months of antituberculous therapy is generally adequate for resolution.

More Related Videos

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy
03:13

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

1.8K
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

18.5K

Related Experiment Videos

Last Updated: May 5, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.3K
Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy
03:13

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

1.8K
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

18.5K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Cerebral tuberculoma is a rare manifestation of tuberculosis, often presenting as a space-occupying lesion in the brain.
  • Diagnosis can be challenging due to non-specific symptoms and normal initial investigations like chest X-rays.
  • Patients typically lack a prior history of tuberculosis.

Purpose of the Study:

  • To report clinical presentations, diagnostic methods, and treatment outcomes of cerebral tuberculoma.
  • To correlate findings with existing literature and emphasize the importance of considering tuberculoma in differential diagnoses.
  • To evaluate the efficacy and duration of antituberculous therapy for intracranial tuberculoma.

Main Methods:

  • Retrospective case series of six patients diagnosed with cerebral tuberculoma over two years.
  • Clinical data, radiological findings (primarily Magnetic Resonance Imaging), and treatment responses were analyzed.
  • Diagnosis was confirmed by Magnetic Resonance Imaging and, in some cases, brain biopsy.

Main Results:

  • Eighty-five percent of patients were over 30 years old, with normal chest X-rays and erythrocyte sedimentation rates.
  • Five patients presented with space-occupying lesion symptoms; none had papilledema.
  • Two patients experienced paradoxical enlargement of lesions during antituberculous therapy, which resolved with continued treatment. Four patients normalized with 12 months of therapy.

Conclusions:

  • Cerebral tuberculoma should be considered in the differential diagnosis of intracranial space-occupying lesions.
  • Magnetic Resonance Imaging is a sensitive tool for diagnosing cerebral tuberculoma.
  • Twelve months of antituberculous treatment is generally sufficient for resolution, and paradoxical enlargement can be managed with continued therapy.