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Drug interactions through binding to cytochrome p 450: the experience with h2-receptor blocking agents

U Klotz1, I W Reimann

  • 1Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie, Auerbachstr. 112, D-7000, Stuttgart 50.

Pharmaceutical Research
|November 27, 2013
PubMed
Summary

Cimetidine drug interactions can be serious, as it binds to cytochrome P450, inhibiting drug metabolism. Ranitidine and oxmetidine do not significantly bind to cytochrome P450, making them safer alternatives with fewer drug interactions.

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