Antiviral and other bioactivities of pyrimidinones

Soluble CD4-PE40 is cytotoxic for a transfected mammalian cell line stably expressing the envelope protein of human immunodeficiency virus (HIV-1), and cytotoxicity is variably inhibited by the sera of HIV-1-infected patients.

AIDS research and human retroviruses·1991

An NMR study of the covalent and noncovalent interactions of CC-1065 and DNA.

Biochemistry·1990

Protection from carcinogen-induced murine bladder carcinoma by interferons and an oral interferon-inducing pyrimidinone, bropirimine.

Cancer research·1990

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065.

Journal of medicinal chemistry·1988

Antitumor activity of pyrimidinones, a class of small-molecule biological response modifiers.

Journal of biological response modifiers·1987

Inhibitory effects of interferon-inducing pyrimidinones on the growth of transplantable mouse bladder tumors.

Cancer research·1986

Neuroregulation as a modulatory force in immune checkpoint inhibitor resistance: mechanistic neuro-immune crosstalk informing biomarker-led diagnosis and targetable therapeutic sensitization.

Pharmacology & therapeutics·2026

Galectin-3 and its inhibitors: Overview and perspectives.

Pharmacology & therapeutics·2026

B-cell precursor acute lymphoblastic leukaemia: Origins, classification, and therapeutic advances.

Pharmacology & therapeutics·2026

Targeting depression: Pharmacological mechanisms and therapeutic targets.

Pharmacology & therapeutics·2026

Apolipoprotein E in spinal cord injury: mechanisms of lipid dysregulation, neuroinflammation, and opportunities for repair.

Pharmacology & therapeutics·2026

Cell death-induced chronic inflammation as a therapeutic target for metabolic dysfunction-associated steatohepatitis.

Pharmacology & therapeutics·2026

Biosynthesis of Active Ginsenoside Aglycone Analogues Using Two Oxidases Mined from Mucor spinosus.

Journal of agricultural and food chemistry·2026

Dialkyl ether synthesis through heteroatom homolytic substitution.

Nature·2026

Programmable remodelling of carbon-nitrogen connectivity in amines.

Nature·2026

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Antiviral and other bioactivities of pyrimidinones

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Soluble CD4-PE40 is cytotoxic for a transfected mammalian cell line stably expressing the envelope protein of human immunodeficiency virus (HIV-1), and cytotoxicity is variably inhibited by the sera of HIV-1-infected patients.

An NMR study of the covalent and noncovalent interactions of CC-1065 and DNA.

Protection from carcinogen-induced murine bladder carcinoma by interferons and an oral interferon-inducing pyrimidinone, bropirimine.

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065.

Antitumor activity of pyrimidinones, a class of small-molecule biological response modifiers.

Inhibitory effects of interferon-inducing pyrimidinones on the growth of transplantable mouse bladder tumors.

Neuroregulation as a modulatory force in immune checkpoint inhibitor resistance: mechanistic neuro-immune crosstalk informing biomarker-led diagnosis and targetable therapeutic sensitization.

Galectin-3 and its inhibitors: Overview and perspectives.

B-cell precursor acute lymphoblastic leukaemia: Origins, classification, and therapeutic advances.

Targeting depression: Pharmacological mechanisms and therapeutic targets.

Apolipoprotein E in spinal cord injury: mechanisms of lipid dysregulation, neuroinflammation, and opportunities for repair.

Cell death-induced chronic inflammation as a therapeutic target for metabolic dysfunction-associated steatohepatitis.

Biosynthesis of Active Ginsenoside Aglycone Analogues Using Two Oxidases Mined from Mucor spinosus.

Dialkyl ether synthesis through heteroatom homolytic substitution.

Programmable remodelling of carbon-nitrogen connectivity in amines.

Related Experiment Videos

Antiviral and other bioactivities of pyrimidinones

Related Concept Videos

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