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Heart failure in patients with normal coronary anatomy: diagnostic algorithm and disease pattern of various
1Cardiology and Nephrology Department, HELIOS Klinikum Berlin and Charite University, Medicine Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.
Insights
Cardiac magnetic resonance (CMR) imaging helps diagnose non-ischemic heart disease in acute heart failure patients when coronary artery disease is unlikely. This review outlines a CMR protocol to guide diagnosis and optimize treatment.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Acute heart failure (AHF) can stem from non-ischemic heart disease (NIHD) in some patients.
- Coronary artery disease (CAD) may be excluded in a subset of AHF cases.
- Accurate diagnosis of NIHD is crucial for effective AHF management.
Purpose of the Study:
- To propose a diagnostic algorithm utilizing cardiac magnetic resonance (CMR) for patients with AHF and suspected NIHD.
- To review the utility of CMR in identifying underlying pathologies in NIHD.
- To discuss diagnostic markers and challenges associated with CMR in NIHD.
Main Methods:
- The review synthesizes current literature on CMR protocols for NIHD.
- It details specific CMR sequences and imaging markers relevant to various NIHD etiologies.
- Diagnostic criteria and potential pitfalls of CMR in this context are examined.
Main Results:
- CMR offers valuable insights into myocardial tissue characteristics, aiding in the differentiation of NIHD.
- Specific CMR findings can identify causes like myocarditis, cardiomyopathies, and infiltrative diseases.
- A structured CMR approach can enhance diagnostic accuracy and guide therapeutic decisions.
Conclusions:
- Cardiac magnetic resonance imaging is a powerful tool for diagnosing non-ischemic heart disease in acute heart failure.
- Implementing a dedicated CMR protocol can elucidate cardiac pathology, optimize patient management, and improve outcomes.
- Further research and standardization of CMR protocols are encouraged for NIHD assessment.
Abstract:
In a subgroup of patients with acute heart failure coronary artery disease can be excluded. To explain symptoms and optimize therapy cardiac magnetic resonance (CMR) imaging can contribute to elucidate the underlying pathology in non-ischemic heart disease. A diagnostic algorithm for the work-up of these patients using CMR is suggested. The review discusses various modules of a dedicated CMR protocol. It explains diagnostic markers and challenges of CMR imaging in non-ischemic heart disease. Based on these suggestions the literature in the field is reviewed.
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