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Post-stroke pathological crying: frequency and correlation to depression.

G Andersen1, K Vestergaard, M Ingeman-Nielsen

  • 1Departments of Neurology, Aalborg, PO Box 365, DK-9100 Aalborg, DenmarkDiagnostic Radiology, Aalborg Hospital, Aalborg, PO Box 365, DK-9100 Aalborg, Denmark.

European Journal of Neurology
|November 29, 2013
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Summary
This summary is machine-generated.

Post-stroke pathological crying is common and linked to mood and depression. This finding strengthens the case for treating pathological crying after a stroke.

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Medicine

Background:

  • Pathological crying (PC) was traditionally viewed as a motor disturbance of emotional affect, independent of mood.
  • Emerging evidence suggests a potential correlation between PC and mood disturbances, particularly depression.

Purpose of the Study:

  • To investigate the relationship between post-stroke pathological crying, mood scores, depression, and lesion characteristics.
  • To determine the incidence and persistence of pathological crying in the first year following stroke.

Main Methods:

  • A cohort of 211 first-ever stroke patients were assessed within 7 days of onset.
  • Follow-up examinations occurred at 1 month, 6 months, and 1 year post-stroke.
  • Computerized tomography (CT) brain scans were utilized for lesion site and size analysis.

Main Results:

  • The overall 1-year incidence of pathological crying was 19%, with 11% persistent at 1 year.
  • Pathological crying significantly correlated with mood scores (p < 0.005) and post-stroke depression (p < 0.005).
  • Correlations were also found with lesion size (p < 0.05), Barthel Index (p < 0.05), Motricity Index (p < 0.005), and intellectual impairment (p < 0.05).

Conclusions:

  • Post-stroke pathological crying is a frequent and persistent condition in a significant patient subset.
  • The strong correlation with mood and depression underscores the psychological component of pathological crying.
  • These findings further support the clinical indication for therapeutic interventions targeting pathological crying post-stroke.