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Updated: May 5, 2026
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Cervical adenocarcinoma identification by testing for chromosomal abnormalities
Janet L Dittus1, Bunyan S Dudley, Madhvi Upender
1From the Department of Gynecologic Oncology, Tennessee Oncology, Nashville, Tennessee (Dr Dudley); and NeoDiagnostix, Rockville, Maryland (Dr Upender and Mr Endress). Dr Dittus is in private practice, Nashville, Tennessee. Dr. Upender is now the CEO of Naveenum, Potomac, Maryland. Mr Endress is a full-time employee and stockholder of NeoDiagnostix, which provided clinical lab testing during the care of the patient. The other authors have no relevant financial interest in the products or companies described in this article.
Abstract:
We report on a case of cervical adenocarcinoma in situ in a 42-year-old woman with a history of human papillomavirus infection. Repeat cytology, human papillomavirus testing, and colposcopy failed to identify the lesion. Testing of the cervical cell DNA identified chromosomal abnormalities, prompting a cervical cone biopsy, which identified adenocarcinoma in situ.
