Related Experiment Video

Updated: Jul 31, 2026

High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity
09:09

High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity

Published on: November 16, 2016

Effects of cell density on drug-induced cell kill kinetics in vitro (inoculum effect)

T Ohnuma, H Arkin, J F Holland

    British Journal of Cancer
    |September 1, 1986
    PubMed

    More Related Videos

    Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method12:03

    Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

    Published on: April 18, 2019

    Comprehensive Analysis of Drug Response using the FLICK Assay09:42

    Comprehensive Analysis of Drug Response using the FLICK Assay

    Published on: June 6, 2025

    Related Concept Videos

    Drug Product Performance: In Vitro–In Vivo Correlation01:20

    Drug Product Performance: In Vitro–In Vivo Correlation

    In pharmaceutical development, it's crucial to establish a predictive in vitro–in vivo correlation (IVIVC) for two or more formulations to gain a comprehensive understanding of release properties. IVIVC reduces the need for costly in vivo studies and facilitates the establishment of meaningful dissolution specifications with significant cost savings and decreased regulatory burden. Furthermore, a meaningful IVIVC should predict Cmax and AUC within 20%, aligning with FDA guidance while adhering...
    Pharmacokinetic–Pharmacodynamic Relationship: Intensity of Dose-Effect Relationship01:23

    Pharmacokinetic–Pharmacodynamic Relationship: Intensity of Dose-Effect Relationship

    Pharmacodynamics explores the relationship between drug concentration and its effect. In a quantal response drug, the duration of action better correlates with drug concentration, while for graded effect drugs, the intensity of response is more relevant. This intensity depends on the dose, drug removal rate, and the region of the concentration–response curve.The concentration–response curve can be divided into three regions. Region 3 (80–100% maximum response) demonstrates that even as drug...