Related Experiment Video
Updated: May 5, 2026
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
On-pump beating-heart versus conventional coronary artery bypass grafting for revascularization in patients with
Bilgehan Erkut1, Ozgur Dag, Mehmet Ali Kaygin
1From the Department of Cardiovascular Surgery, Erzurum Training and Research Hospital, Erzurum, Turkey.
Insights
The on-pump beating-heart technique for coronary artery bypass grafting offers better outcomes for patients with left ventricular dysfunction, showing reduced mortality and improved heart function compared to conventional methods.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Heart Function Improvement
Background:
- Coronary artery disease (CAD) with left ventricular dysfunction presents unique surgical challenges.
- Evaluating surgical techniques for CAD is crucial for improving patient outcomes.
Purpose of the Study:
- To compare on-pump beating-heart coronary artery bypass grafting (CABG) with conventional CABG requiring cardioplegic arrest.
- To assess the impact of these techniques on survival, morbidity, and left ventricular function in patients with low ejection fraction.
Main Methods:
- A comparative study of 131 patients undergoing CABG between August 2009 and June 2012.
- Group I: Conventional CABG with cardioplegic arrest. Group II: On-pump beating-heart CABG without cardioplegic arrest.
- Outcomes measured included mortality, perioperative myocardial infarction, low cardiac output syndrome, and improvement in left ventricular ejection fraction.
Main Results:
- Both techniques showed a significant reduction in mortality (p < 0.001).
- On-pump beating-heart CABG (Group II) had lower rates of perioperative myocardial infarction and low cardiac output syndrome compared to conventional CABG (Group I) (p < 0.05).
- Improvement in left ventricular function was significantly better in the on-pump beating-heart group.
Conclusions:
- On-pump beating-heart CABG is a preferred method for myocardial revascularization in patients with left ventricular dysfunction.
- This technique offers an acceptable alternative to conventional CABG due to lower postoperative mortality and morbidity.
Background:
We sought to evaluate the effects of on-pump beating-heart versus conventional coronary artery bypass grafting techniques requiring cardioplegic arrest in patients with coronary artery disease with left ventricular dysfunction.
Methods:
We report the early outcomes associated with survival, morbidity and improvement of left ventricular function in patients with low ejection fraction who underwent coronary artery bypass grafting between August 2009 and June 2012. Patients were separated into 2 groups: group I underwent conventional coronary artery bypass grafting and group II underwent an on-pump beating-heart technique without cardioplegic arrest.
Results:
In all, 131 patients underwent coronary artery bypass grafting: 66 in group I and 65 in group II. Left ventricular ejection fraction was 26.6% ± 3.5% in group I and 27.7% ± 4.7% in group II. Left ventricular end diastolic diameter was 65.6 ± 3.6 mm in group I and 64.1 ± 3.2 mm in group II. There was a significant reduction in mortality in the conventional and on-pump beating-heart groups (p < 0.001). Perioperative myocardial infarction and low cardiac output syndrome were higher in group I than group II (both p < 0.05). Improvement of left ventricular function after the surgical procedure was better in group II than group I.
Conclusion:
The on-pump beating-heart technique is the preferred method for myocardial revascularization in patients with left ventricular dysfunction. This technique may be an acceptable alternative to the conventional technique owing to lower postoperative mortality and morbidity.
