Related Experiment Video
Updated: May 5, 2026
Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Surgical anterior ventricular endocardial restoration performed with total arterial revascularization: serial 5-year
Ho Young Hwang1, Jun Sung Kim2, Kwang Ree Cho3
1Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, South Korea.
Insights
Surgical anterior ventricular endocardial restoration improved left ventricular (LV) function and reduced volumes long-term. Preserved arterial graft patency is key to maintaining these positive LV remodeling outcomes.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Imaging
Background:
- Surgical anterior ventricular endocardial restoration (SAVER) is a complex procedure aimed at improving left ventricular (LV) function.
- Total arterial revascularization (TAR) is often performed concurrently to ensure optimal coronary blood supply.
Purpose of the Study:
- To evaluate the long-term changes in LV function and volumes following SAVER.
- To assess the impact of SAVER on LV remodeling and patient survival.
Main Methods:
- A cohort of 63 patients undergoing SAVER and TAR were assessed using echocardiography and myocardial single-photon emission computed tomography (SPECT) up to 5 years post-surgery.
- Coronary angiography was performed at 5 years to evaluate arterial graft patency.
Main Results:
- Operative mortality was 7.9%. Echocardiography showed sustained improvement in LV ejection fraction and reduced LV volumes at 5 years.
- SPECT confirmed gradual LV ejection fraction improvement and stable reduced LV volumes.
- Arterial graft patency was high (95.7%) in the left coronary territory, with 10-year survival at 59.2%.
Conclusions:
- SAVER leads to sustained improvements in LV ejection fraction and reduced LV volumes.
- High arterial graft patency likely contributes to the preserved LV function post-SAVER.
- The procedure offers significant long-term benefits for LV remodeling and patient survival.
Objective:
We evaluated the changes in left ventricular (LV) function and volumes after surgical anterior ventricular endocardial restoration.
Methods:
A total of 63 patients who had undergone surgical anterior ventricular endocardial restoration and total arterial revascularization were included. Echocardiography and myocardial single photon emission computed tomography were performed to examine LV function and volumes preoperatively, early postoperatively, and annually thereafter to 5 years after surgery. Coronary angiography was performed at 5 years postoperatively.
Results:
Operative mortality was 7.9% (5 of 63). Echocardiograms performed before discharge demonstrated a significantly improved LV ejection fraction that was maintained at 5 years, significantly decreased early postoperative LV end-diastolic and end-systolic volume indexes that were slightly increased at 1 year and then maintained at 5 years, and early postoperative decrement of the stroke volume index that had disappeared at 1 year and had not reappeared by 5 years. Postoperative myocardial single photon emission computed tomography showed an LV ejection fraction that had gradually improved until 2 years and was maintained at 5 years, significantly decreased LV end-diastolic and end-systolic volume indexes that were maintained at 5 years, and a stroke volume index that was unchanged until 2 years and slightly increased at 3 to 4 years. The arterial graft patency rate in the left coronary territory was 95.7% (67 of 70) at 5 years. The 10-year overall survival and adverse event-free rate were 59.2% and 61.2%, respectively.
Conclusions:
Improved LV ejection fraction and reduced volume indexes were maintained and the stroke volume index had not decreased at 5 years after the procedure. Preserved patency of the arterial grafts might have an important role in maintaining improved LV function.
More Related Videos
14:14Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
08:42Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
