Related Experiment Video
Updated: May 5, 2026

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
Surgical thrombectomy and simultaneous stenting for deep venous thrombosis caused by iliac vein compression syndrome
Kimihiro Igari1, Toshifumi Kudo, Takahiro Toyofuku
1Division of Vascular and Endovascular Surgery, Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Insights
Surgical thrombectomy with stenting effectively treats deep venous thrombosis (DVT) caused by May-Thurner syndrome (MTS), restoring venous patency and relieving acute symptoms in patients with iliofemoral DVT.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiovascular Medicine
Background:
- May-Thurner syndrome (MTS) involves left iliac vein compression by the right common iliac artery, increasing deep venous thrombosis (DVT) risk.
- Acute iliofemoral DVT presents a significant clinical challenge requiring effective treatment strategies.
Purpose of the Study:
- To evaluate the outcomes of surgical thrombectomy combined with simultaneous stenting for treating DVT secondary to MTS.
- To assess the efficacy and safety of this combined approach in restoring venous flow.
Main Methods:
- A cohort of 8 patients with acute iliofemoral DVT and diagnosed MTS underwent surgical thrombectomy and stenting.
- Follow-up included duplex sonography to assess stent patency over a mean period of 16 months.
Main Results:
- The procedure achieved successful re-canalisation of iliofemoral veins in all patients.
- No perioperative mortality or pulmonary embolism occurred; 2 patients experienced early rethrombosis.
- Six out of eight patients maintained patent stents during the follow-up period.
Conclusions:
- Venous thrombectomy with simultaneous stenting is a potent treatment for acute iliofemoral DVT caused by MTS.
- This technique effectively restores venous patency and alleviates acute symptoms associated with MTS-related DVT.
Purpose:
Iliac vein compression syndrome (May-Thurner syndrome) is characterized by left iliac vein obstruction secondary to compression by the right common iliac artery against the fifth-lumbar vertebra, which increases incidence of deep venous thrombosis (DVT). We treated the patients with DVT due to May-Thurner syndrome (MTS) by surgical thrombectomy and simultaneous stenting, and this study is to evaluate the outcomes of this procedure.
Methods:
From January 2009 to December 2011, a total of 8 patients underwent surgical thrombectomy with stenting. All patients were admitted for acute DVT involving the left iliofemoral segment, and diagnosed MTS. Patients were followed-up, and stent patency was assessed by means of duplex sonography.
Results:
In all patients, the procedure was successful in achieving re-canalisation of the iliofemoral veins at the end of the operation. Perioperatively, there was no mortality and there was no case of clinically detected pulmonary embolism. Rethrombosis occurred within seven days of operation in 2 patients. During the follow-up period (mean; 16 months), 6 of 8 patients kept patent stents.
Conclusion:
Venous thrombectomy with simultaneous stenting is a potent technique to treat acute iliofemoral DVT due to MTS. This technique can restore venous patency and provide relief of the acute symptoms.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis I: Introduction
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis IV: Nursing Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

