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Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration

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Chirality in Nature

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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.

Prochirality

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The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...

Chirality

Chirality

Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...

Regioselectivity and Stereochemistry of Hydroboration

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A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
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Regioselectivity of Electrophilic Additions to Alkenes: Markovnikov's Rule

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If a set of reactants can yield multiple constitutional isomers, but one of the isomers is obtained as the major product, the reaction is said to be regioselective. In such reactions, bond formation or breaking is favored at one reaction site over others.
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Updated: May 5, 2026

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy

Published on: May 27, 2018

Chirality-driven wettability switching and mass transfer.

Guangyan Qing¹, Taolei Sun

¹State Key Laboratory of Advanced Technology for Materials, Synthesis and Processing, Wuhan University of Technology, 122 Luoshi Road, Wuhan 430070 (P. R. China).

Angewandte Chemie (International Ed. in English)

|November 29, 2013

Summary

This summary is machine-generated.

Chiral molecules can control surface wettability, leading to new chiral material designs. Smart polymers translate chiral signals into distinct, reversible wettability switching, offering novel material properties.

Keywords:

chirality hydrogen bonds materials science polymers

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Area of Science:

Materials Science
Supramolecular Chemistry
Polymer Science

Background:

Chiral molecules offer unique properties for advanced material design.
Surface wettability is a critical parameter in material performance and application.
Smart polymers can respond to external stimuli, enabling dynamic material properties.

Purpose of the Study:

To investigate the use of chiral molecules for enantioselective control of surface wettability.
To explore the potential of smart polymers in translating chiral information into macroscopic material responses.
To demonstrate a novel wettability switching mechanism driven by chirality.

Main Methods:

Utilizing smart polymers capable of reversible conformational transitions.
Designing chiral molecular systems to interact with polymer surfaces.
Characterizing surface wettability changes in response to chiral stimuli.
Investigating the mechanism of chiral signal amplification.

Main Results:

Demonstrated enantioselective control over surface wettability using chiral molecules.
Achieved distinct wettability switching behavior driven by chirality.
Showcased the ability of smart polymers to amplify weak chiral signals into macroscopic effects.
Confirmed the reversibility of the conformational transition and its impact on wettability.

Conclusions:

Chiral molecules can effectively regulate the surface wettability of materials.
Smart polymers provide a versatile platform for developing chiral-responsive materials.
This approach offers new insights into designing advanced chiral materials with tunable surface properties.