Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

31
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
31
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

906
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
906
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

50
Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
50
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

1.2K
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
1.2K
Cholecystitis01:20

Cholecystitis

32
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
32

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Rash Decision: Mycoplasma-Induced Mucositis in a Young Adult.

Cureus·2026
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Assessing prevalence and risk factors for REM sleep behavior disorder among patients with inflammatory bowel disease.

NPJ Parkinson's disease·2025
Same author

Affective schemas: Acquisition, updating, and inference.

Emotion (Washington, D.C.)·2025
Same author

Characterizing Parkinson's Disease Clinical and Biomarker Interactions in REM Sleep Behavior Disorder.

medRxiv : the preprint server for health sciences·2025
Same author

Histological Analysis of Bridge-Enhanced ACL Restoration (BEAR) Tissue in Ligament Retears.

Orthopaedic journal of sports medicine·2025
Same journal

Upadacitinib salvage for refractory immune checkpoint inhibitor colitis complicated by cytomegalovirus infection.

BMJ case reports·2026
Same journal

<b>Severe hypokalaemia and secretory diarrhoea secondary to a vasoactive intestinal peptide-secreting tumour (VIPoma</b>).

BMJ case reports·2026
Same journal

Intraductal oncocytic papillary neoplasm of the pancreas.

BMJ case reports·2026
Same journal

Post-extubation pneumothorax following bougie-assisted endotracheal tube exchange.

BMJ case reports·2026
Same journal

Cardiac tamponade secondary to hypothyroidism.

BMJ case reports·2026
Same journal

Unmasking a rare contrast reaction: acute non-cardiogenic pulmonary oedema after iohexol injection.

BMJ case reports·2026
See all related articles

Related Experiment Video

Updated: May 5, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

1.7K

Chilblain lupus erythematosus.

Sapna Patel1, Faddy Hardo

  • 1King's College Hospital, London, UK.

BMJ Case Reports
|November 29, 2013
PubMed
Summary
This summary is machine-generated.

Chilblain lupus erythematosus, a rare skin condition, presents with cold-induced lesions. This case study highlights successful treatment with hydroxychloroquine.

More Related Videos

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

943
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.7K

Related Experiment Videos

Last Updated: May 5, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

1.7K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

943
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.7K

Area of Science:

  • Dermatology
  • Rheumatology
  • Immunology

Background:

  • Chilblain lupus erythematosus (CLE) is a rare variant of chronic cutaneous lupus erythematosus.
  • It manifests as painful, cold-induced skin lesions, primarily affecting acral areas.
  • Distinguishing CLE from other chilblain conditions is crucial for appropriate management.

Observation:

  • A case of CLE was diagnosed in a patient presenting with characteristic purple, oedematous plaques on acral regions.
  • The clinical presentation was consistent with significant exposure to cold.
  • Diagnostic confirmation utilized the established Mayo Clinic Diagnostic Criteria.

Findings:

  • The patient's chilblain lupus erythematosus was successfully diagnosed using the Mayo Clinic Diagnostic Criteria.
  • Treatment with hydroxychloroquine resulted in significant improvement of the skin lesions.
  • This demonstrates the efficacy of hydroxychloroquine in managing CLE.

Implications:

  • This case underscores the importance of the Mayo Clinic Diagnostic Criteria for accurate CLE diagnosis.
  • Hydroxychloroquine is confirmed as an effective therapeutic option for chilblain lupus erythematosus.
  • Further research into optimal management strategies for CLE is warranted.