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Induction of Ocular Surface Inflammation and Collection of Involved Tissues
Published on: August 4, 2022
Ocular surface disorders in intensive care unit patients
Tuba Berra Saritas1, Banu Bozkurt, Baris Simsek
1Anesthesiology and Reanimation Department, Meram Medical Faculty, Necmettin Erbakan University, 42080 Konya, Turkey.
Intensive care unit (ICU) patients face high risks of eye problems like corneal abrasions and infections due to reduced blinking and exposure. Early ophthalmologist consultation is crucial for diagnosing and treating these ocular surface disorders in ICU patients.
Area of Science:
- Ophthalmology
- Critical Care Medicine
Background:
- Intensive care unit (ICU) patients are vulnerable to ocular surface issues, including corneal abrasions and infectious keratitis.
- Factors contributing to these risks include impaired eyelid closure, diminished blink reflex, and increased exposure to pathogens.
Purpose of the Study:
- To retrospectively evaluate ocular surface problems in patients with prolonged ICU stays (>7 days) requiring ophthalmology consultation.
- To identify the prevalence and types of ocular surface disorders in this high-risk patient population.
Main Methods:
- Retrospective analysis of 40 patients (26 men, 14 women; mean age 40.1 years) admitted to the ICU for over 7 days.
- Ophthalmological examination including assessment of conjunctival hyperemia, secretions, corneal staining, filaments, and Schirmer's test.
- Correlation of ocular findings with mechanical ventilation, sedation, and inotrope use.
Main Results:
- Common findings included conjunctival hyperemia (56.25%), mucopurulent/purulent secretions (36.25%), and corneal staining (15%).
- Keratitis was diagnosed in 10% of patients, successfully treated with topical antibiotics.
- Reduced tear production (Schirmer's test <5 mm/5 min) was observed in 40% of patients, with no significant difference based on ventilation, sedation, or inotropes.
Conclusions:
- ICU patients exhibit a high prevalence of ocular surface disorders, including dry eye and potential infections.
- Ophthalmological consultation is recommended for early detection and management of these conditions to prevent vision-threatening complications.
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