Related Experiment Video
Updated: May 5, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
Published on: January 16, 2019
Congenital long-QT syndrome in a Nigerian child: a case report
1Department of Paediatrics, University of Abuja Teaching Hospital, Gwagwalada, Abuja.
Case Report:
We describe the clinical manifestation and the challenges of diagnosing Long QT syndrome, type 1 (LQTS1), in an 8-year old girl who presented at the Paediatric Cardiology Clinic with syncopal attacks following dancing and excitement. Her initial ECG showed normal QT interval of 380msec (QTc=440 msec), but later, increased to 410 msec (QTc=520 msec) following epinephrine challenge test.
Conclusion:
The challenges with the diagnosis of LQTS1 in children in resource-constrained setting and the need for vigilance in children with syncopal attacks and other cardiac events with normal QT intervals on an electrocardiogram are thus highlighted.
More Related Videos
Related Concept Videos
Mitral Stenosis I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Mitral Stenosis II: Clinical features and Diagnostic Tests
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Dysrhythmias I: Introduction
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....

