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Related Experiment Video

Updated: May 5, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
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Vacuum phenomenon: Clinical relevance.

Ishan Gohil1, Joel A Vilensky, Edward C Weber

  • 1Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, Indiana.

Clinical Anatomy (New York, N.Y.)
|November 30, 2013
PubMed
Summary
This summary is machine-generated.

The vacuum phenomenon (VP) is often mistaken for serious joint pathology but is usually benign. Recognizing true VP prevents misdiagnosis and ensures appropriate patient care.

Keywords:
joint painjoint pathologyvacuum jointvacuum phenomenon

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Area of Science:

  • Radiology
  • Anatomy
  • Medical Imaging

Background:

  • Vacuum phenomenon (VP) is an anatomical finding that can complicate joint pathology diagnosis.
  • VP is observed across various imaging modalities, including radiography, CT, and MRI.
  • It is frequently associated with degenerative joint disease but also occurs in other conditions.

Purpose of the Study:

  • To review the literature on the vacuum phenomenon.
  • To clarify its underlying mechanisms, associated pathologies, and clinical significance.
  • To establish diagnostic criteria and a workup algorithm for VP.

Main Methods:

  • Literature review to synthesize information on VP.
  • Analysis of imaging characteristics (CT, GRE-MRI, multipositional views).
  • Development of diagnostic criteria and a clinical algorithm.

Main Results:

  • VP formation is explained by gas solubility, pressure-volume relationships, and physiology.
  • CT, GRE-MRI, and multipositional views are optimal for visualizing VP.
  • VP is often underreported, particularly outside the spine, and can be mistaken for serious pathology.

Conclusions:

  • VP is a common, often benign finding that requires accurate identification.
  • Distinguishing VP from other joint pathologies is crucial to avoid misdiagnosis and inappropriate treatment.
  • VP should be considered in the differential diagnosis of joint pain, especially in elderly patients.