Audit of missed or delayed antimicrobial drugs

Julia Wright1

  • 1East and South East England Specialist Pharmacy Services.

Nursing Times
|December 3, 2013
PubMed

Insights

Omitted medication doses remain a frequent issue despite patient safety reports. A collaborative audit found 13% of antimicrobial doses were omitted, highlighting the need for targeted interventions and leadership to improve patient care.

Area of Science:

  • Patient Safety
  • Medication Management
  • Antimicrobial Stewardship

Background:

  • Omitted and delayed medication doses continue to be a significant patient safety concern, despite previous reports and awareness initiatives.
  • The Francis report underscored the potential impact of medication errors on patient care, necessitating further investigation into their occurrence.

Purpose of the Study:

  • To investigate the incidence and patterns of omitted antimicrobial doses through a multicentre point-incident collaborative audit.
  • To identify the extent to which antimicrobial doses are omitted and to inform targeted interventions for improvement.

Main Methods:

  • A multicentre point-incident collaborative audit was conducted.
  • Patient records for 6,062 individuals, encompassing 21,825 prescribed antimicrobial doses, were reviewed.

Main Results:

  • A total of 13% of all prescribed antimicrobial doses were found to be omitted.
  • While some omissions may be clinically justified, a significant proportion may occur without acceptable reason, requiring organizational attention.

Conclusions:

  • Sustained improvements in medication safety require national initiatives, robust local nursing leadership, and multidisciplinary collaboration.
  • The study provides tools and insights that can assist healthcare organizations in addressing omitted medication doses and enhancing patient care.

Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
2.0K
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
79
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
2.3K
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
346
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
106
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
118