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Lack of association between brain-derived neurotrophic factor Val66Met polymorphism and aggressive behavior in
Xuan Guan1, Zai-Quan Dong2, Yuan-Yuan Tian3
1School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan, China.
Abstract:
We investigated the association of the Val66Met gene polymorphism in the Brain-Derived Neurotrophic Factor (BDNF) gene with aggressive behavior among Southern Han Chinese schizophrenia patients. We used polymerase chain reaction-restriction fragment length polymorphism to determine the genotypes and the Modified Overt Aggression Scale (MOAS) to measure aggressive behavior. No significant differences in genotype or allele distribution of Val66Met were identified between aggressive and non-aggressive schizophrenia patients.
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