[Post-splenectomy complications in primary immune thrombocytopenia. Literature review and preventive measures]

M Mahévas1, H Coignard-Biehler2, M Michel1

  • 1Service de médecine interne, centre de référence des cytopénies auto-immunes de l'adulte, université Paris Est Créteil (UPEC), CHU Henri-Mondor, Assistance publique-Hôpitaux de Paris, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000 Créteil, France.

La Revue De Medecine Interne
|December 3, 2013
PubMed

Management of primary immune thrombocytopenia (ITP) has changed, and clinical practice broadens the use of thrombopoietin receptor agonists and anti-CD20 antibody as options for second-line therapy, as alternative to splenectomy. Splenectomy remains a successful, definitive curative treatment. The purpose of this review about the complications of the splenectomy, in the context of ITP, is to increase the awareness of clinicians towards the preventive measures, which are often not correctly applied.

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