Related Experiment Video
Updated: May 5, 2026
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Microwave ablation of osteoid osteomas using dynamic MR imaging for early treatment assessment: preliminary
Michael Kostrzewa1, Patricius Diezler1, Henrik Michaely1
1Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Purpose:
To evaluate the efficacy of microwave ablation for osteoid osteomas by using dynamic contrast-enhanced magnetic resonance (MR) imaging in early treatment assessment.
Materials And Methods:
Ten patients (two female, eight male; mean age, 28 y; range, 16-47 y) presenting with osteoid osteomas were treated between June 2010 and December 2012 with the use of computed tomography (CT)-guided microwave ablation. Osteoid osteomas were found at the femoral neck (n = 4), tibia (n = 3), calcaneus (n = 1), navicular bone (n = 1), and dorsal rib (n = 1). Dynamic contrast-enhanced MR imaging at 3.0 T was performed 1 day before microwave ablation and again after ablation. The procedure was considered successful if the signal intensity (SI) of the lesion on MR imaging decreased by at least 50% and the patient was pain-free within 1 week of intervention.
Results:
All patients were pain-free within 1 week after microwave ablation and remained so during the 6 months of follow-up. No major or minor complications developed. On average, SI of the lesions decreased by 75% (range, 55.5%-89.1%) after treatment. The difference in lesion SI before versus after ablation was significant by t test (P < .0001; confidence interval, 120.26-174.96) and Wilcoxon test (P = .0020).
Conclusions:
Microwave ablation treatment of osteoid osteoma was highly successful, without any complications observed. Dynamic contrast-enhanced MR imaging is a useful tool for diagnosing osteoid osteoma and evaluating treatment.
