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[Effect of hyperbaric oxygenation on the extrasystole in ischemic heart disease patients]
Insights
Hyperbaric oxygen therapy (HBO) initially improves cardiac rhythm in coronary patients with extrasystole. However, prolonged HBO treatment may worsen arrhythmia, suggesting a limited therapeutic window for this cardiac condition.
Area of Science:
- Cardiology
- Hyperbaric Medicine
- Electrophysiology
Background:
- Chronic extrasystole is a common cardiac arrhythmia in patients with coronary artery disease.
- Hyperbaric oxygenation (HBO) involves breathing pure oxygen in a pressurized chamber, with potential therapeutic applications.
Purpose of the Study:
- To investigate the effect of single-session and course-based hyperbaric oxygenation on cardiac rhythm in coronary patients.
- To determine the optimal duration for HBO therapy to achieve antiarrhythmic effects without adverse events.
Main Methods:
- Study included 82 coronary patients diagnosed with chronic extrasystole.
- Patients underwent hyperbaric oxygenation (HBO) in single sessions or as a treatment course.
- Electrocardiogram (ECG) monitoring was performed during HBO sessions and via 24-hour Holter recordings before and after treatment.
Main Results:
- A positive therapeutic effect on cardiac rhythm was observed in all patients after 5-6 HBO sessions.
- Ectopic activity increased in 15.4% of patients, and remained unchanged in 17% after a complete HBO course.
- A correlation was found between in-chamber ECG monitoring (from session 7) and 24-hour ECG recordings.
Conclusions:
- Initial HBO sessions (5-6) demonstrate a positive antiarrhythmic effect in coronary patients with extrasystole.
- Prolonged HBO treatment (beyond 7 sessions) may lead to an aggravation of arrhythmia in some individuals.
- The antiarrhythmic benefit of a complete HBO course is questionable, with potential for increased ectopic activity.
Abstract:
A study of the effect of hyperbaric oxygenation (HBO), applied as single sessions or a treatment course, on cardiac rhythm in 82 coronary patients with chronic extrasystole demonstrated positive therapeutic effect to be achieved after the first 5 or 6 HBO sessions in all patients. Further treatment may provoke an aggravation of arrhythmia in some patients. Positive antiarrhythmic effect of a complete HBO course is doubtful, where ectopic activity is increased following the 7th session. There is a correlation between the results of ECG monitoring from the hyperbaric chamber, from session 7 onwards, and 24-hour ECG recording before and after a HBO course. As shown by 24-hour ECG monitoring, positive effect was obtained in 67% of patients with ventricular extrasystole, the number of ventricular extrasystoles remained basically unchanged after a HBO course in 17%, and ectopic activity increased in 15.4%.