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Published on: July 14, 2023
Temporal evolution of event-related desynchronization in acute stroke: a pilot study
Chayanin Tangwiriyasakul1, Rens Verhagen2, Wim L C Rutten3
1Neural Engineering, Institute for Biomedical Technology and Technical Medicine (MIRA), University of Twente, Enschede, The Netherlands; Clinical Neurophysiology, Institute for Biomedical Technology and Technical Medicine (MIRA), University of Twente, Enschede, The Netherlands.
Objective:
Assessment of event-related desynchronization (ERD) may assist in predicting recovery from stroke and rehabilitation, for instance in BCI applications. Here, we explore the temporal evolution of ERD during stroke recovery.
Methods:
Ten stroke patients and eleven healthy controls were recruited to participate in a hand movement task while EEG was being recorded. Four measurements were conducted in eight patients within four months. We quantified changes of ERD using a modulation strength measure, S(m), which represents an area and amplitude of ERD.
Results:
7/8 patients showed good recovery. Absence-or-reduction of ipsilesional modulation was initially found in stroke patients but not in the healthy controls. In the patient group, two evolutions were found in 6/8 patients: a significant increase in ipsilesional S(m); and a decreasing trend in contralesional S(m). In the only non-recovery patient, absence of ipsilesional modulation was observed, while his contralesional S(m) increased with time after stroke.
Conclusion:
The two evolutions presumably reflect the reorganization of brain networks and functional recovery after acute stroke. The significant increase of ipsilesional S(m) in patients with a good recovery suggests an important role of this hemisphere during recovery.
Significance:
Improved understanding of ERD in acute stroke may assist in prognostication and rehabilitation.
