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Computer-aided diagnosis of diabetic retinopathy: a review

Muthu Rama Krishnan Mookiah1, U Rajendra Acharya, Chua Kuang Chua

  • 1Department of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore 599489 Singapore.

Computers in Biology and Medicine
|December 3, 2013
PubMed

Keywords:
Computer-aided diagnosisFundus imagingImage processingPattern classificationRetinaRetinopathy

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration...
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