Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

56
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...
56
Sex Linked Disorders01:43

Sex Linked Disorders

28.9K
28.9K
Sex-linked Disorders01:43

Sex-linked Disorders

95.2K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
95.2K
Pleiotropy01:33

Pleiotropy

31.3K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
31.3K
Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

46
Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the...
46
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

2.0K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Postoperative imaging following spinal surgery for traumatic injuries].

Radiologie (Heidelberg, Germany)·2025
Same author

[Use of IL-1 inhibitors in the treatment of familial Mediterranean fever in pediatric rheumatology].

Zeitschrift fur Rheumatologie·2025
Same author

Cytotoxic activity of liposomal <i>Thymus capitatus</i> essential oil on HT-29 human colorectal cancer cell line.

Die Pharmazie·2024
Same author

Effects of glucagon as a neurohormone on the central nervous system and glucose homeostasis.

European review for medical and pharmacological sciences·2024
Same author

Nanoencapsulation of <i>Origanum vulgare</i> essential oil into liposomes with anticancer potential.

Die Pharmazie·2022
Same author

[COVID-19: neurological manifestations-update : What we know so far].

Der Radiologe·2021
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2022
Same journal

Der Radiologe·2022
See all related articles

Related Experiment Video

Updated: May 5, 2026

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

5.8K

[Sturge-Weber syndrome].

W Reith1, U Yilmaz, A Zimmer

  • 1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg/Saar, Deutschland, Wolfgang.Reith@uniklinikum-saarland.de.

Der Radiologe
|December 3, 2013
PubMed
Summary
This summary is machine-generated.

Sturge-Weber syndrome (SWS) is a rare congenital neurocutaneous disorder affecting the brain, skin, and eyes. This condition involves venous angiomatosis, leading to symptoms like seizures and port-wine stains.

More Related Videos

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

2.1K
A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

7.9K

Related Experiment Videos

Last Updated: May 5, 2026

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

5.8K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

2.1K
A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

7.9K

Area of Science:

  • Neurology
  • Genetics
  • Dermatology

Context:

  • Sturge-Weber syndrome (SWS) is a rare congenital neurocutaneous disorder.
  • Affects approximately 1 in 50,000 births.
  • Characterized by venous angiomatosis impacting the brain, skin, and eyes.

Purpose:

  • To provide a comprehensive overview of Sturge-Weber syndrome.
  • To detail the key clinical manifestations and pathological features.
  • To highlight the diagnostic and management considerations for SWS.

Summary:

  • Intracranial leptomeningeal angiomatosis, primarily in occipital and posterior parietal lobes, is a hallmark.
  • Facial port-wine stains (nevus flammeus), typically along the trigeminal nerve V1 and V2, are common.
  • Associated symptoms include seizures, glaucoma, cognitive impairment, and neurological deficits like hemiparesis.

Impact:

  • Enhances understanding of SWS pathophysiology and clinical presentation.
  • Aids clinicians in diagnosing and managing patients with SWS.
  • Provides a foundation for future research into SWS treatments.