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Challenges in measuring medication adherence: experiences from a controlled trial.

Kay Stewart¹, Kevin P Mc Namara, Johnson George

¹Centre for Medicine Use and Safety, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC, 3052, Australia, kay.stewart@monash.edu.

International Journal of Clinical Pharmacy

|December 3, 2013

Summary

This summary is machine-generated.

Measuring medication adherence is complex. Combining dispensing records with other methods is crucial for identifying patients needing help with antihypertensive medication adherence.

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Area of Science:

Pharmacology
Health Services Research

Background:

Medication adherence is critical for managing hypertension.
Accurate measurement of adherence is challenging due to the lack of a universal gold standard.

Purpose of the Study:

To evaluate a community pharmacy-based intervention for improving adherence to antihypertensive medication within the Hypertension Adherence Program in Pharmacy (HAP-P) trial.
To assess various objective and subjective adherence measures and their effectiveness in identifying nonadherent patients.

Main Methods:

A randomized controlled trial was conducted, implementing a community pharmacy-based intervention.
Multiple adherence measures were employed, including the Morisky score, TABS score, MedsIndex, and Medicines Possession Ratio.
Data mining software was utilized to identify potentially nonadherent patients from dispensing records.

Main Results:

Objective and subjective adherence measures yielded varying results, impacting the confidence in study conclusions.
A significant number of patients identified as potentially nonadherent through dispensing records were found to be adherent using the self-reported Morisky scale.
Discrepancies between different adherence measurement methods were observed.

Conclusions:

Relying solely on dispensing records may inaccurately identify patients needing adherence support.
Supplementing dispensing data with other assessment methods is essential for accurately identifying individuals requiring assistance to improve antihypertensive medication adherence.
Intervention targeting for adherence improvement requires a multi-faceted approach to patient identification.