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Published on: September 15, 2017
A success story in congenital adrenal hyperplasia
Alka Kriplani1, Amol Lunkad, Nutan Agarwal
1Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, Room No. 3081, Teaching Block, Ansari Nagar (E), New-Delhi, 110029 India.
Abstract:
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders characterized by enzyme defects in adrenal steroidogenic pathways. CAH due to 21-hydroxylase deficiency accounts for 95 % of cases. This case was diagnosed to have simple virilizing type of CAH and started on dexamethasone, and underwent genitoplasty and clitoroplasty at 25 years of age, then was married 3 years after surgery and conceived spontaneously 2 years after marriage, to deliver a healthy male baby. Thus, proper diagnosis and treatment with steroids and genitoplasty can give females with CAH a normal sexual, normal menstrual, and reproductive function.
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