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Detection of left ventricular asynchrony and its relationship with the Tei index in patients with coronary artery

Serkan Ozturk1, Selim Ayhan, Yusuf Aslantas

  • 1Faculty of Medicine, Department of Cardiology, Abant Izzet Baysal University, Bolu;

Experimental and Clinical Cardiology
|December 3, 2013
PubMed

Insights

Patients with coronary artery ectasia (CAE) show left ventricular (LV) systolic asynchrony. This asynchrony correlates with the Tei index and thrombolysis in myocardial infarction frame count (TFC), with the Tei index being an independent risk factor.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Physiology

Background:

  • Coronary artery ectasia (CAE) is a complex vascular condition.
  • Left ventricular (LV) systolic asynchrony may impact cardiac function in CAE patients.
  • Tissue Doppler imaging (TDI) and tissue synchronization imaging (TSI) are valuable tools for assessing cardiac mechanics.

Purpose of the Study:

  • To evaluate left ventricular (LV) systolic asynchrony in patients with coronary artery ectasia (CAE) using tissue synchronization imaging (TSI).
  • To assess the relationship between LV systolic asynchrony, the Tei index, and thrombolysis in myocardial infarction frame count (TFC) in CAE patients.
  • To determine if the Tei index is an independent risk factor for LV systolic asynchrony in CAE.

Main Methods:

  • Fifty patients with CAE and 40 controls underwent conventional echocardiography and TDI.
  • LV systolic and diastolic function were assessed.
  • Intra-LV systolic asynchrony was evaluated using tissue synchronization imaging (TSI), measuring parameters like Ts-SD-12 and Ts-12.

Main Results:

  • Patients with CAE exhibited significantly higher Tei index values compared to controls.
  • LV systolic asynchrony parameters (Ts-SD-12, Ts-12, Ts-SD-6, Ts-6) were significantly prolonged in CAE patients.
  • A significant positive correlation was observed between Ts-SD-12 and the Tei index in CAE patients (r=0.841; P<0.001).
  • Mean TFC positively correlated with Ts-SD-12 and the Tei index (P<0.05).

Conclusions:

  • Patients with coronary artery ectasia (CAE) demonstrate significant left ventricular (LV) systolic asynchrony via TSI.
  • LV systolic asynchrony is closely related to the Tei index and mean thrombolysis in myocardial infarction frame count (TFC).
  • The Tei index is identified as an independent risk factor for LV systolic asynchrony in CAE.
Abstract

Keywords:
Coronary artery ectasiaLeft ventricular asynchronyTei index

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