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Rheumatoid factor and hearing loss.

V Ashok Murthy1, J Mohan Kumar

  • 1Department of ENT, PES Institute of Medical Science and Research, Kuppam, AP 517425 India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|December 3, 2013
PubMed
Summary
This summary is machine-generated.

Rheumatoid factor, a marker for rheumatoid arthritis, is significantly associated with hearing loss. A study found 27% of patients with rheumatoid factor had abnormal hearing, indicating a strong link.

Keywords:
Autoimmune ear diseaseDistortion product otoacoustic emissionHearing lossRheumatoid factor

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Area of Science:

  • Rheumatology
  • Otolaryngology
  • Audiology

Background:

  • Rheumatoid factor is an autoantibody commonly associated with rheumatoid arthritis.
  • Hearing loss is a potential extra-articular manifestation of autoimmune diseases.
  • The link between rheumatoid factor and subclinical hearing impairment requires further investigation.

Purpose of the Study:

  • To investigate the association between the presence of rheumatoid factor and hearing loss.
  • To determine the prevalence of hearing impairment in patients with positive rheumatoid factor.

Main Methods:

  • A prospective study was conducted involving 85 patients with positive rheumatoid factor.
  • Patients underwent pure tone audiometry and Distortion Product Otoacoustic Emissions (DPOAE) screening.
  • Data was collected from patients in the Departments of Medicine and Orthopedics.

Main Results:

  • All 85 patients had a positive rheumatoid factor.
  • Pure tone audiograms were normal in all patients.
  • Distortion Product Otoacoustic Emissions (DPOAE) were absent in 23 patients (27%).
  • The absence of DPOAE in 27% of rheumatoid factor-positive patients was statistically significant.

Conclusions:

  • A significant association exists between rheumatoid factor and hearing loss.
  • Distortion Product Otoacoustic Emissions (DPOAE) may detect early-stage hearing impairment in rheumatoid factor-positive individuals.
  • Further research is warranted to elucidate the mechanisms underlying rheumatoid factor-associated hearing loss.