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A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
Febrile seizures
Insights
Febrile seizures are common in children and usually benign. This review covers the evaluation, management, and prognosis of simple and complex febrile seizures, including febrile status epilepticus.
Area of Science:
- Pediatrics
- Neurology
- Epilepsy
Background:
- Febrile seizures are the most common seizure type in children, affecting 2-5% of the pediatric population.
- Despite being generally benign and self-limiting, febrile seizures are a common cause of emergency room visits and parental distress.
- The American Academy of Pediatrics (AAP) updated guidelines in 2011 define febrile seizures based on age, fever threshold, and absence of central nervous system infection.
Purpose of the Study:
- To review the current understanding of febrile seizures.
- To outline the evaluation and management strategies for simple and complex febrile seizures.
- To discuss the prognosis of febrile seizures, including febrile status epilepticus.
Main Methods:
- Literature review of febrile seizures.
- Analysis of clinical practice guidelines from the American Academy of Pediatrics (AAP).
- Discussion of diagnostic criteria, classification, and treatment approaches.
Main Results:
- Febrile seizures are classified as simple or complex.
- Evaluation focuses on excluding other causes of seizures and fever.
- Management strategies vary based on seizure type and patient factors.
Conclusions:
- Febrile seizures are common and typically benign childhood events.
- Accurate diagnosis and appropriate management are crucial.
- Understanding the prognosis, including for febrile status epilepticus, is important for clinical practice and parental reassurance.
Abstract:
Febrile seizures are the most common form of childhood seizures, affecting 2% to 5% of children. They are considered benign and self-limiting; however, a febrile seizure is a terrifying event for most parents, and is one of the most common causes of trips to the emergency room. A febrile seizure is "an event in infancy or childhood, usually occurring between 3 months and 5 years of age, associated with fever but without evidence of intracranial infection or defined cause." This definition excludes seizures with fever in children who have had a prior afebrile seizure. In 2011, The American Academy of Pediatrics (AAP) published a clinical practice guideline defining a febrile seizure as "a seizure accompanied by fever (temperature ≥ 100.4°F or 38°C by any method), without central nervous system infection, that occurs in infants and children 6 through 60 months of age." Febrile seizures are further classified as simple or complex. This article reviews the evaluation, management, and prognosis of simple and complex seizures, including febrile status epilepticus.
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