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Updated: May 5, 2026

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Published on: January 2, 2009
An overview of epigenetics in nursing
Ashley Erin Clark1, Maria Adamian, Jacquelyn Y Taylor
1Yale University, School of Nursing, 400 West Campus Drive, Orange, CT 06477, USA.
Epigenetic research, focusing on gene expression changes without altering DNA, is crucial for nursing practice. Nurses can lead and integrate this research across various health areas for improved patient outcomes.
Area of Science:
- Genomic Science
- Biochemistry
- Nursing Research
Background:
- Epigenetic changes influence gene expression without altering DNA sequence.
- The nursing profession is well-positioned to advance epigenetic research and its clinical applications.
- Understanding epigenetics is vital for addressing complex health conditions.
Purpose of the Study:
- To review current epigenetic nursing research across diverse health domains.
- To elucidate the relationship between epigenetic research and contemporary nursing practice.
- To provide actionable recommendations and resources for epigenetic nursing research.
Main Methods:
- Literature review of major epigenetic studies in nursing.
- Synthesis of findings from studies in childbirth, preeclampsia, metabolic syndrome, cancer immunotherapy, and pain.
- Identification of research gaps and future directions.
Main Results:
- Epigenetic nursing research is expanding, with notable studies in critical care areas.
- Significant links exist between epigenetic modifications and health outcomes in studied populations.
- Current research highlights the potential for nursing interventions to influence epigenetic factors.
Conclusions:
- Epigenetic research offers a promising frontier for nursing science and practice.
- Nurses should actively engage in and lead epigenetic research to enhance patient care.
- Further research and integration of epigenetic findings are recommended for clinical practice.
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