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Updated: May 5, 2026

Visualization of UV-induced Replication Intermediates in E. coli using Two-dimensional Agarose-gel Analysis
Published on: December 21, 2010
Replicating damaged DNA in eukaryotes
Nimrat Chatterjee1, Wolfram Siede
1Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030.
Abstract:
DNA damage is one of many possible perturbations that challenge the mechanisms that preserve genetic stability during the copying of the eukaryotic genome in S phase. This short review provides, in the first part, a general introduction to the topic and an overview of checkpoint responses. In the second part, the mechanisms of error-free tolerance in response to fork-arresting DNA damage will be discussed in some detail.
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